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Getting bit by mosquitoes is never fun, and it can be downright deadly if they happen to be carrying diseases like malaria. Mankind’s quest to keep this nuisance under control, however well-meaning it may be, appears to have had the opposite of its intended effect as a new study shows how mosquitoes have evolved a type of genetic shield to protect themselves from chemical pesticides.

In an article published in Trends in Parasitology, researchers from University of California, Riverside, review the interesting genetic changes that have given the Anopheles mosquitoes that spread malaria to humans a new brand of pesticide resistance. Their findings show how human interventions have sparked an evolutionary response that allows them to resist the very pesticides that were designed to keep them at bay.

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