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CRISPR-Cas9 is the talk of the town in biotechnology. There is a huge amount of public interest in the possibilities provided by this new genome editing technology, and many are hoping CRISPR could eventually cure most genetic disease, with positive impact for millions.

But a bioRxiv preprint of a new study has a potentially disturbing result: many people may already be immune to the most widely used forms of CRISPR.

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