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Mexican police found a multi-drug shipment that included an astonishing 100 pounds (45.5 kilograms) of the synthetic opioid fentanyl in a vehicle near the city of Ensenada in Baja California, officials said Thursday.

Fentanyl can be fatal in doses of just a few milligrams. To put the size of the haul in perspective, a seizure last year of 4.5 pounds (2 kilograms) of fentanyl in Columbus, Ohio, was said by prosecutors to be enough to potentially kill the entire population of the city of 860,000 people.

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